ODCs

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1 OMIM reference -
1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
18 signs/symptoms

Pseudohypoaldosteronism type 2E

ACTH-independent macronodular adrenal hyperplasia


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	CUL3	(0.63)	ARMC5

Citations in the biomedical literature:

Pseudohypoaldosteronism type 2E		ACTH-independent macronodular adrenal hyperplasia
	Synonym(s): - PHA2E		Synonym(s): - AIMAH - Adrenocorticotropic hormone-independent macronodular adrenal hyperplasia - Corticotropin-independent macronodular adrenal hyperplasia

	Classification (Orphanet): - Rare circulatory system disease - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Rare endocrine disease - Rare infertility

	Classification (ICD10): - Diseases of the circulatory system -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: - Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: any age Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references

ACTH-independent macronodular adrenal hyperplasia
	Very frequent - Cortico-adrenal hyperplasia / hypersecretion - Cushingoid morphotype - Failure to thrive / difficulties for feeding in infancy / growth delay - Round face - Thin skin - Truncal obesity Frequent - Asthenia / fatigue / weakness - Bruisability - Chronic arterial hypertension - Diabetes mellitus - Hirsutism / hypertrichosis / Increased body hair - Humour troubles / anxiety / depression / apathy / euphoria / irritability - Metrorrhagia / menorrhagia / hemorrhagic cycles / hyper / poly / spanio / dysmenorrhea - Muscle weakness / flaccidity - Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets - Urinary / renal lithiasis / kidney stones / nephritic colic Occasional - Autosomal dominant inheritance - Meningioma
Pseudohypoaldosteronism type 2E
(no data available)